Getting rid of spyware is like sanitizing latrines after a cholera epidemic. You want to use every tool you have, bleach, Lysol, a steam genereator, blowtorch and sometimes even a bull dozer. Microsoft actually recommends the bull dozer, format and reload. With some effort you may be able to reach a comfortable level of sanitation with less intensive methods.

One kinder gentler method is Spybot Search and Destroy. Download it from FileHippo, install it, update, immunize and scan for problems. If the updates fail, try a different mirror. Keep trying until you see the green check mark along side each update. Repeat "Immunize" after every update.

If Spybot says it can't remove offending entries, see Knoppix and follow the procedure there.

Turn on Mode, Advanced and you get a lot more opportunity for intellectual investment, some of it rewarding.